The Effectiveness of Additional Tomato (Solanum lycopersicum) Water Extract as Antiagregation of Thrombocytes in Whole Blood on The Number of Thrombocytes and Thrombocytes Antiagregation

Ganjar Noviar, Eem Hayati, Yenni Wahyuni, Asep Iin Nur Indra

Abstract


In hypertensive patients, there is hyperaggregation of platelets. Platelet accumulation and thrombus formation due to hyperaggregation are important in the pathogenesis of cardiovascular and cerebrovascular diseases. Tomato (Solanum lycopersicum) is a horticultural product that contains adenine which is useful for preventing platelet aggregation. The purpose of this study was to determine the effectiveness of minimal concentrations of aqueous extract of tomato (Solanum lycopersicum) as anti-platelet aggregation in whole blood on platelet count and platelet aggregation. This study was a quasi-experimental study by observing platelet counts using a hematology analyzer. In addition, platelet aggregation was measured using the velaskar method with aspirin (control) 5 ppm and with the addition of aqueous extract of Tomato (Solanum lycopersicum) with concentrations of 5, 10 and 15 ppm. The research data obtained is presented in tabular form and then processed using the Normality Test and One Way ANOVA Test. The results showed that the water extract of tomato (Solanum lycopersicum) was effective as an anti-platelet aggregation in whole blood on platelet count and platelet aggregation with a minimum concentration of 5 ppm

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References


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Ruang Jurnal Lantai 2, Gedung Cipto Mangunkusumo, Fakultas Kedokteran, UPN Veteran Jakarta, Indonesia.

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