Hubungan Antara Sifilis dengan Kejadian HIV-AIDS pada Kelompok LSL
Abstract
HIV (Human Immunodeficiency Virus) terus menjadi masalah kesehatan global yang serius, dengan
dampak signifikan terutama pada kelompok Lelaki yang berhubungan Seks dengan Lelaki (LSL).
Meskipun AIDS bukan lagi penyakit dengan angka kematian tertinggi, infeksi baru dan kematian terkait
AIDS tetap tinggi, khususnya di komunitas yang rentan seperti gay, biseksual, dan laki-laki yang
berhubungan seks dengan laki-laki. Penelitian ini bertujuan untuk mengetahui hubungan antara sifilis
dan peningkatan risiko terkena HIV/AIDS pada kelompok LSL. Penelitian ini bersifat kuantitatif
observasional, menggunakan data sekunder Surveilans Terpadu Biologis dan Perilaku (STBP) yang
berasal dari Kementerian Kesehatan Republik Indonesia pada bagian Direktorat Pencegahan dan
Pengendalian Penyakit Menular (P2PM) tahun 2019 dengan desain potong lintang atau cross-sectional.
Analisis yang dilakukan berupa analisis univariat (distribusi frekuensi) bivariat (uji statistik chi-square)
dan multivariat menggunakan Regresi Logistic dengan melihat nilai p pada analisis bivariat. Pada hasil
akhir regresi logistik menunjukan bahwa LSL yang memiliki status reaktif sifilis beresiko 4,5 kali lebih
tinggi mempunyai status reaktif HIV dibandingkan dengan LSL yang tidak memiliki status reaktif sifilis.
References
Abara, W. E. et al. (2016) ‘Syphilis
Trends among Men Who Have Sex with
Men in the United States and Western
Europe : A Systematic Review of Trend
Studies Published between 2004 and
’, pp. 1–19. doi:
1371/journal.pone.0159309.
Aung, E. T. et al. (2019) ‘Incidence and
Risk Factors for Early Syphilis Among
Men Who Have Sex With Men in
Australia , 2013 – 2019 : A
Retrospective Cohort Study’, Open
Forum Infectious Diseases, 10(2), pp.
–10. doi: 10.1093/ofid/ofad017.
Bunyasi, E. W., & Coetzee, D. J.
(2017). Relationship between
socioeconomic status and HIV
infection: Findings from a survey in the
Free State and Western Cape Provinces
of South Africa. BMJ Open, 7(11), 1–9.
https://doi.org/10.1136/bmjopen-2017-
Chow, E. P. F. et al. (2017) ‘Increased
Syphilis Testing of Men Who Have Sex
With Men : Greater Detection of
Asymptomatic Early Syphilis and
Relative Reduction in Secondary
Syphilis’, 65, pp. 389–395. doi:
1093/cid/cix326.
Fernandes, A. and Ervianti, E. (2015)
‘Secondary Syphilis in Human
Immunodeficiency Virus ( HIV ) -
Infected Men Who Have Sex with Men
( MSM ): A Case Report’, pp. 75–84.
Gilbert, L., Dear, N., Esber, A.,
Iroezindu, M., Bahemana, E., Kibuuka,
H., Owuoth, J., Maswai, J., Crowell, T.
A., Polyak, C. S., Ake, J. A.,
Bartolanzo, D., Reynolds, A., Song, K.,
Milazzo, M., Francisco, L.,
Mankiewicz, S., Schech, S., Golway,
A., ... Olomi, W. (2021). Prevalence
and risk factors associated with HIV
and syphilis co-infection in the African
Cohort Study: a cross-sectional study.
BMC Infectious Diseases, 21(1), 1–7.
https://doi.org/10.1186/s12879-021-
-6
Guanghua, L. et al. (2018) ‘HIV,
syphilis and behavioral risk factors
among men who have sex with men in a
drug-using area of southwestern China’,
(March).
Kates, J., & Levi, J. (2007). Insurance
coverage and access to HIV testing and
treatment: Considerations for
individuals at risk for infection and for
those with undiagnosed infection.
Clinical Infectious Diseases,
(SUPPL. 4), 255–260.
https://doi.org/10.1086/522547
Lemeshow, S. et al. 1990, ―Adequacy
of Sample Size in Health Studies,‖
WHO, 47(1), p. 347. doi:
2307/2532527.
Lin, R. et al. (2021) ‘Breaking Down
Barriers to HIV Care for Gay and
Bisexual Men and Transgender
Women : The Advocacy and Other
Community Tactics ( ACT ) Project’,
AIDS and Behavior, 25(8), pp. 2551–
doi: 10.1007/s10461-021-03216-
w.
Mahmud, S. et al. (2023) ‘Prevalence of
HIV and syphilis and their co-infection
among men having sex with men in
Asia : A systematic review and meta-
analysis’, Heliyon, 9(3), p. e13947. doi:
1016/j.heliyon.2023.e13947.
Nikolopoulos, G. K. (2022) ‘Recent
HIV Infection : Diagnosis and Public
Health Implications’.
Nishijima, T. et al. (2016) ‘Incidence
and Risk Factors for Incident Syphilis
among HIV-1-Infected Men Who Have
Sex with Men in a Large Urban HIV
Clinic in Tokyo , 2008 − 2015’, pp. 1–
doi: 10.1371/journal.pone.0168642.
Park, H. et al. (2016) ‘Risk Factors
Associated with Incident Syphilis in a
Cohort of High-Risk Men in Peru’, pp.
–10. doi:
1371/journal.pone.0162156.
Rocha, G. M. et al. (2023) ‘Strategies to
increase HIV testing among men who
have sex with men and transgender
women : an integrative review’. doi:
1186/s12879-023-08124-z.
Shilaih, M. et al. (2017) ‘Factors
associated with syphilis incidence in the
HIV-infected in the era of highly active
antiretrovirals’, 2(December 2016).
Solomon, H., Moraes, A. N., Williams,
D. B., Fotso, A. S., Duong, Y. T.,
Ndongmo, C. B., Voetsch, A. C., Pate,
H., Lupoli, K., McAuley, J. B.,
Mulundu, G., Kasongo, W., &
Mulenga, L. (2020). Prevalence and
correlates of active syphilis and HIV co-
Infection among sexually active persons
aged 15-59 years in Zambia: Results
from the Zambia Population-based HIV
Impact Assessment (ZAMPHIA) 2016.
PLoS ONE, 15(7 July), 1–11.
https://doi.org/10.1371/journal.pone.02
Tran, B. X. et al. (2019) ‘Understanding
Global HIV Stigma and
Discrimination : Are Contextual Factors
Sufficiently Studied?’
Tumwine, J. K. (2022) ‘Sexual
reproductive health , NCDs and
infectious diseases’, 22(1).
UNAIDS (2022) ‘Global HIV
Statistics’
UNAIDS (2023) ‘The Path that Ends
AIDS: 2023 UNAIDS Global AIDS
Update’
UNAIDS (2023) ‘UNAIDS Data 2023’
Wu, M. Y., Gong, H. Z., Hu, K. R.,
Zheng, H. Y., Wan, X., & Li, J. (2021).
Effect of syphilis infection on HIV
acquisition: A systematic review and
meta-analysis. Sexually Transmitted
Infections, 97(7), 525–533.
https://doi.org/10.1136/sextrans-2020-
Xu, Y. et al. (2022) ‘Trends in HIV
Prevalence and HIV-Related Risk
Behaviors Among Male Students Who
Have Sex With Men From 2016 to 2020
in Nanjing , China : Consecutive Cross-
Sectional Surveys’, 10(April), pp. 1–9.
doi: 10.3389/fpubh.2022.806600
Refbacks
- There are currently no refbacks.